Once dismissed as a passing skin concern of adolescence, acne is now recognized as a chronic, relapsing inflammatory condition that affects people across all ages and skin types. It impacts not only the skin—but also self-esteem, mental health, and long-term skin quality.

At the heart of this evolution in understanding lies a critical shift: Acne is not just about oil and bacteria—it begins with inflammation.

Recent studies confirm that inflammation precedes comedone formation, highlighting the role of Caveolin-1 (CAV1)—a protein deeply involved in cellular signaling and inflammation regulation. This insight reshapes how we diagnose, prevent, and treat acne at its earliest stages.